What is PRF? : Although PRP and PRF may be used similarly, the way both are prepared and how they work are a bit different. It was developed in France by Choukroun et al (2001). PRF Injections in Costa Mesa, CA offers a higher concentration of platelets while preserving the fibrin matrix without the need for anticoagulants. This matrix serves to retain the platelets, allowing for a gradual release in the injected areas. Once released, the platelets yield longer-lasting results in diminishing fine lines, wrinkles, and facial folds. An initial consultation is crucial in determining the most suitable treatment for your specific concerns and considering other relevant factors. PRF is entirely autologous, containing collagen type-1 lymphocytes alongside growth factors. This promotes natural reconstruction, boost collagen production, rejuvenates the skin, improves tissue quality, tightens the skin, and aids in lifting the face, neck, chest, and hands. It addresses skin discoloration, diminishes wrinkles, alleviates dark bags and hollow under eyes, and reduces nasolabial folds and tear troughs. Additionally, it assists with lip volumization and and addresses concerns to related to hair loss. 

This approach to facial rejuvenation embraces a more natural method, utilizing your body’s own resources to activate growth factors and collagen production. This leads to the filling of lines, a revitalized complexion, and improved under-eye area discoloration and tear troughs.

PRF jumpstarts cell renewal and initiates collagen and elastin production, resulting in a lifting and volumizing effect on the skin. This transformative process is set in motion when PRF is introduced, prompting the skin to regenerate and revitalize itself with the aid of growth factors.

Where is PRF Used?: 

Major Skin Areas (face, head, hands, & chest for micro-needling)

Under Eyes

Lips

Cheeks

Temples

Chin

Scalp (for hair restoration)

Contraindications: Smokers (it inhibits the body’s ability to heal). Acute and chronic infections, severe metabolic and systemic disorders, abnormal platelet function, blood disorders, chronic liver pathology, people on anti-coagulation therapy, people undergoing chemotherapy treatments, cancer patients, underlying sepsis and systemic use of coricosteroids within 2 weeks of the procedure.

Recommendation: We recommend a series of 3 PRF treatments spaced approximately 4-6 weeks apart for optimal results. Hence, we advise once every 6 months of annually upkeep injection once your series is finished. Consideration for Hyaluronic Acid fillers may be given 3-6 months after your third PRF injection. It may take up to 3-4 moths to observe long-term benefits, such as improved skin quality, increased collagen production, and enhanced skin tightening, which can last from 6-12 months. The initial volume boost will endure for 1 to 3 weeks. Two vials of your own blood will be used to stimulate your own cells to regenerate.

Expectations During the Procedure:  During your treatment appointment, ensure you are adequately hydrated. We will collect two vials of blood, which will then be placed in a centrifuge. Following the spinning process, the PRF is isolated from the other blood components and extracted from the top of the vial. As the blood is centrifuged, you will be seated with numbing medication to minimize any discomfort. The PRF will be administered using a blunt-tipped cannula immediately after the spinning process is finished. The entire procedure for PRF Under Eye injections typically lasts about 40 minutes from start to finish.

Expectations After the Procedure: Following the treatment, it is normal to observe some swelling or bruising under the eyes. You might also notice a slight fullness in this area for about 3-5 days post-injection, along with a potential yellowish tint to the skin until the PRF naturally resolves. The effects of the treatment typically begin to manifest around the 1-2 month mark, as the structures and collagen beneath the eyes continue to regenerate. In most cases, there is minimal to no discomfort after PRF injections.

What Potential Issues or Complications May Arise From the PRF Treatment?: As with any type of injection, there is a potential for bruising, discomfort, and redness due to the needle used during the procedure. At BABYFACE, we prioritize your comfort and provide a topical numbing agent for the process. The PRF is administered to the under-eye area and tear trough using a blunt-tipped cannula, offering a needle-free technique that ensures precise application and significantly reduces the likelihood of bruising. Given that we are introducing a fluid-like substance under the eye, some degree of swelling or puffiness is anticipated, typically lasting around 3-5 days.

Is the PRF injection considered safe?: PRF is highly secure. The injections entail minimal side effects or risks as they exclusively involve your own blood without any additional additives or medications.

What is the duration of effectiveness for PRF Treatment?: Given that initial results typically manifest within 4-8 weeks post-PRF injection, with continued improvement over the following 3-6 months, most outcomes endure for approximately 1.5 years following the last injection. Consequently, we suggest an annual maintenance injection once your series is concluded.

The Platelet-Rich Fibrin Gel :EZ PRF gel is a 100% natural biostimulating injectable that utilizes the body’s natural proteins and growth factors to improve skin tone and texture while treating deep tear troughs, lines and wrinkles, volume loss, and more. EZ Gel technique uses the latest generation of Smart Blood

Concentrates to generate a complex Fibrin Matrix rich in Platelets, Leukocytes and Mesenchymal stem cells. For 10-12 days this results in the constant release of Growth factors and interleukins which accelerate tissue healing and regenerating processes.

PRF Plasma Injections in Costa Mesa, CA is effective in most cases; no guarantees can be made that a specific patient will benefit from this procedure. Additionally, the nature of cosmetic procedure may require a patient to return for numerous visits in order to achieve the desired results or to determine whether PRF Gel may not be completely effective at treating the particular condition. The healing process takes time and the final result won’t be readily visible for many months.*

POSSIBLE RISKS AND SIDE EFFECTS ASSOCIATED WITH PRF
1. DISCOMFORT: Discomfort may be experienced during blood draw where there is a slight pinch to insert the needle for the blood collection as well as during the procedure if PRF is injected into the site.
Repeat injections may be necessary. 

2. BRUISING, SWELLING, INFECTION: With any minimally invasive procedure, bruising of the treated
area may occur. Additionally, there may be swelling noted. Finally, skin infection is rare, but always a possibility with any injection or incision into the skin. 

3. SCARRING: Scar at entry point is extremely rare but must always be considered a possibility when entering the skin. Delayed wound healing and/or scarring may occur. 

4. CONTRAINDICATIONS: Smokers may have less response to this treatment as toxins in smoke block the response of the Stem Cells. Cell death or Fibrosis may occur.

***Nevertheless, PRF injections are typically not recommended for individuals who are on blood thinners, have a blood clotting disorder, collagen vascular disease, an active infection, viral infection such as hepatitis A,B,C,D, Cancer or metastatic disease • An active infection, A low platelet count,  Pregnant/Breastfeeding, or immunosuppressive conditions such as HIV, Ataxia-telangiectasia
Complement deficiencies
DiGeorge syndrome
Hypogammaglobulinemia
Job syndrome
Leukocyte adhesion defects
Agammaglobulinemia
Wiskott-Aldrich syndrome, lupus, etc .***

5. There may be some variation I achieving the results requested as everyone’s body type is different and may have a different response. No guarantees or warrantees with respect to final outcome or its longevity can be offered.
TREATMENT

6 .You may take pain medication such as Tylenol.

7. A numbing cream is applied to the area of treatment.

8. Approximately 10 cc of whole blood is drawn from your arm.

9. The tubes of blood are centrifuged to separate the component cells. Platelets, Leukocytes and
Mesenchymal stem cells are separated and used for this procedure.

10. The liquid is then transferred into a syringe and injected using a tiny needle.

11. ADDITIONAL PROCEDURES MAY BE NECESSARY. In some situations, it may not be possible to achieve optimal results with a single procedure and other procedures may be necessary. The practice of medicine is not an exact science. Although good results are expected, there cannot be any guarantee or warranty expressed or implied on the results that may be obtained.